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Many adults stop GLP-1 therapy within a year with low restart rates, analysis finds

GLP-1 receptor agonists were developed for glycemic control. The cardiovascular outcome data has since reframed how cardiologists need to think about this drug class entirely. Across LEADER, SUSTAIN-6, REWIND, and SELECT, GLP-1

In the ACHIEVE-1 phase 3 trial, the oral small-molecule GLP-1 receptor agonist orforglipron significantly reduced the glycated hemoglobin level over a period of 40 weeks in adults with early type 2 diabetes.

Updated evidence on cardiovascular and renal effects of GLP-1 receptor agonists and combination therapy with SGLT2 inhibitors and finerenone: a narrative review and perspectives | Cardiovascular Diabetology | Springer Nature Link

Advances in GLP-1 receptor agonists for pain treatment and their future potential | The Journal of Headache and Pain | Springer Nature Link

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